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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GUCY1B1Guanylate cyclase 1 soluble subunit beta 1. (594 aa)    
Predicted Functional Partners:
GUCY1A1
Guanylate cyclase 1 soluble subunit alpha 1.
  
0.999
ENSCAPP00000007529
annotation not available
   
 0.945
PDE5A
Phosphodiesterase 5A.
   
 0.927
ENPP3
Ectonucleotide pyrophosphatase/phosphodiesterase 3.
     
 0.918
ENTPD8
Ectonucleoside triphosphate diphosphohydrolase 8.
   
 
  0.908
ENTPD3
Ectonucleoside triphosphate diphosphohydrolase 3.
   
 
  0.908
NUDT2
Nudix hydrolase 2.
     
 0.907
PDE2A
Phosphodiesterase 2A.
   
 0.893
PRKG1
Protein kinase cGMP-dependent 1.
   
 0.881
PDE10A
Phosphodiesterase 10A.
   
 0.877
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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