Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADAMTS10ADAM metallopeptidase with thrombospondin type 1 motif 10. (1062 aa)    
Predicted Functional Partners:
FBN1
Fibrillin 1.
    
 0.818
ADAMTS7
ADAM metallopeptidase with thrombospondin type 1 motif 7.
    
 0.763
LTBP1
Latent transforming growth factor beta binding protein 1.
    
 0.684
LTBP2
Latent transforming growth factor beta binding protein 2.
    
 0.680
LTBP3
Latent transforming growth factor beta binding protein 3.
    
 0.674
POFUT2
Protein O-fucosyltransferase 2.
     
 0.662
FBN2
Fibrillin 2.
    
 0.641
MFAP4
Microfibril associated protein 4.
      
 0.567
B3GLCT
Beta 3-glucosyltransferase.
    
 0.566
ADAMTS17
ADAM metallopeptidase with thrombospondin type 1 motif 17.
    
 0.559
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (16%) [HD]