Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ATF4Activating transcription factor 4. (332 aa)    
Predicted Functional Partners:
CREBBP
CREB binding protein.
    
 0.996
DDIT3
DNA damage inducible transcript 3.
   
 0.996
EP300
E1A binding protein p300.
    
 0.996
ATF3
Activating transcription factor 3.
    
 0.994
ENSCAPP00000009603
annotation not available
   
 0.992
TRIB3
Tribbles pseudokinase 3.
   
 0.983
EIF2S1
Eukaryotic translation initiation factor 2 subunit alpha.
    
 0.982
CREB1
cAMP responsive element binding protein 1.
    
 0.979
FOS
Fos proto-oncogene, AP-1 transcription factor subunit.
    
 0.977
ATF6B
Activating transcription factor 6 beta.
     
 0.961
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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