Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NSMCE2NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. (248 aa)    
Predicted Functional Partners:
SMC5
Structural maintenance of chromosomes 5.
    
 0.999
NSMCE1
NSE1 homolog, SMC5-SMC6 complex component.
    
 0.999
SMC6
Structural maintenance of chromosomes 6.
    
 0.999
NSMCE4A
NSE4 homolog A, SMC5-SMC6 complex component.
    
 0.998
ENSCAPP00000013457
annotation not available
   
 0.959
ZNF597
Zinc finger protein 597.
    
   0.959
ENSCAPP00000008632
annotation not available
    
 0.939
ENSCAPP00000010990
annotation not available
    
 0.939
MAGEL2
MAGE family member L2.
    
 0.939
MRPL45
Mitochondrial ribosomal protein L45.
    
 0.937
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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