Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
UHRF2Ubiquitin like with PHD and ring finger domains 2. (710 aa)    
Predicted Functional Partners:
DNMT1
DNA methyltransferase 1.
  
 0.988
PCNA
Proliferating cell nuclear antigen.
   
 
 0.971
HDAC1
Histone deacetylase 1.
   
 
 0.963
CDYL
Chromodomain Y like.
      
 0.949
ZC3H10
Zinc finger CCCH-type containing 10.
      
 0.949
ENSCAPP00000015638
annotation not available
    
 
 0.934
CDK2
Cyclin dependent kinase 2.
   
 
 0.920
FBXL4
F-box and leucine rich repeat protein 4.
      
 0.918
USP7
Ubiquitin specific peptidase 7.
    
 
 0.914
DNMT3A
DNA methyltransferase 3 alpha.
    
 
 0.860
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: medium (54%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.