Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MPEG1Macrophage expressed 1. (693 aa)    
Predicted Functional Partners:
PLEKHA8
Pleckstrin homology domain containing A8.
      
 0.661
PRF1
Perforin 1.
      
 0.572
SCARB1
Scavenger receptor class B member 1.
      
 0.564
GPNMB
Glycoprotein nmb.
   
  
 0.540
SPI1
Spi-1 proto-oncogene.
   
  
 0.511
PLEKHA3
Pleckstrin homology domain containing A3.
      
 0.500
MAPKBP1
Mitogen-activated protein kinase binding protein 1.
      
 0.454
RGS5
Regulator of G protein signaling 5.
      
 0.454
TTC25
Tetratricopeptide repeat domain 25.
      
 0.411
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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