Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PPM1FProtein phosphatase, Mg2+/Mn2+ dependent 1F. (434 aa)    
Predicted Functional Partners:
FEM1A
Fem-1 homolog A.
   
 0.855
ENSCAPP00000015322
annotation not available
   
 0.855
LATS1
Large tumor suppressor kinase 1.
    
   0.785
CAMK2G
Calcium/calmodulin dependent protein kinase II gamma.
    
 0.725
WDR90
WD repeat domain 90.
    
  0.717
CUL2
Cullin 2.
     
 0.702
TRAF7
TNF receptor associated factor 7.
   
 0.683
CAMK1
Calcium/calmodulin dependent protein kinase I.
    
 0.676
TONSL
Tonsoku like, DNA repair protein.
  
 0.663
FGD1
FYVE, RhoGEF and PH domain containing 1.
      
 0.657
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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