Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TMEM87BTransmembrane protein 87B. (444 aa)    
Predicted Functional Partners:
CCDC186
Coiled-coil domain containing 186.
   
  
 0.594
CASC4
Cancer susceptibility 4.
      
 0.569
ACER1
Alkaline ceramidase 1.
      
 0.568
TM9SF3
Transmembrane 9 superfamily member 3.
      
 0.561
TEPSIN
TEPSIN adaptor related protein complex 4 accessory protein.
      
 0.555
VTI1A
Vesicle transport through interaction with t-SNAREs 1A.
      
 0.549
PLEKHB2
Pleckstrin homology domain containing B2.
      
 0.538
ACER2
Alkaline ceramidase 2.
      
 0.531
SNRNP48
Small nuclear ribonucleoprotein U11/U12 subunit 48.
      
 0.524
ENSCAPP00000000127
annotation not available
      
 0.520
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (24%) [HD]