Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
WWP1WW domain containing E3 ubiquitin protein ligase 1. (619 aa)    
Predicted Functional Partners:
ITCH
Itchy E3 ubiquitin protein ligase.
   
  0.994
SMURF1
SMAD specific E3 ubiquitin protein ligase 1.
    
  0.975
KLF5
Kruppel like factor 5.
    
 0.975
WBP2
WW domain binding protein 2.
    
 
 0.972
SMURF2
SMAD specific E3 ubiquitin protein ligase 2.
    
  0.971
DVL2
Dishevelled segment polarity protein 2.
    
 0.971
ENSCAPP00000008686
annotation not available
    
 0.968
ENSCAPP00000002730
annotation not available
    
 0.966
WWP2
WW domain containing E3 ubiquitin protein ligase 2.
   
   0.963
ENSCAPP00000004927
annotation not available
    
 
 0.961
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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