STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRNPPrion protein. (244 aa)    
Predicted Functional Partners:
FYN
FYN proto-oncogene, Src family tyrosine kinase.
    
 0.967
STIP1
Stress induced phosphoprotein 1.
    
 0.967
NCAM1
Neural cell adhesion molecule 1.
   
 0.951
HSPA5
Heat shock protein family A (Hsp70) member 5.
    
 0.944
ENSCAPP00000007313
annotation not available
    
  0.931
CSNK2A2
Casein kinase 2 alpha 2.
    
  0.931
LAMC1
Laminin subunit gamma 1.
    
  0.926
APP
Amyloid beta precursor protein.
   
 0.922
CAV3
Caveolin 3.
     
 0.915
NCAM2
Neural cell adhesion molecule 2.
   
 0.910
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.