Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HFEHomeostatic iron regulator. (278 aa)    
Predicted Functional Partners:
TFRC
Transferrin receptor.
    
 0.999
TFR2
Transferrin receptor 2.
    
 0.998
HJV
Hemojuvelin BMP co-receptor.
     
 0.989
ENSCAPP00000006521
annotation not available
    
 0.938
BMPR1A
Bone morphogenetic protein receptor type 1A.
   
 0.925
BMPR1B
Bone morphogenetic protein receptor type 1B.
   
 0.913
RGMB
Repulsive guidance molecule BMP co-receptor b.
     
 0.899
RGMA
Repulsive guidance molecule BMP co-receptor a.
     
 0.899
HAMP
Hepcidin antimicrobial peptide.
   
  
 0.881
LTF
Lactotransferrin.
    
 0.867
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.