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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EBF3EBF transcription factor 3. (339 aa)    
Predicted Functional Partners:
UFD1
Ubiquitin recognition factor in ER associated degradation 1.
    
 
 0.685
PLAA
Phospholipase A2 activating protein.
    
   0.671
VCP
Valosin containing protein.
    
 0.634
LHX2
LIM homeobox 2.
   
 
 0.617
EEF1G
Eukaryotic translation elongation factor 1 gamma.
    
   0.511
DOLK
Dolichol kinase.
    
   0.504
ZNF423
Zinc finger protein 423.
   
 
 0.504
PPARG
Peroxisome proliferator activated receptor gamma.
     
 0.498
ENSCAPP00000008628
annotation not available
    
 0.482
ENSCAPP00000011047
annotation not available
    
 
 0.479
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.