Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CERS2Ceramide synthase 2. (336 aa)    
Predicted Functional Partners:
ENSCAPP00000011430
annotation not available
    
 0.967
DEGS1
Delta 4-desaturase, sphingolipid 1.
   
 0.964
ASAH1
N-acylsphingosine amidohydrolase 1.
    
 0.961
SMPD1
Sphingomyelin phosphodiesterase 1.
     
 0.958
ACER2
Alkaline ceramidase 2.
    
 0.958
ACER1
Alkaline ceramidase 1.
    
 0.957
SGMS1
Sphingomyelin synthase 1.
     
 0.956
KDSR
3-ketodihydrosphingosine reductase.
     
 0.956
ENSCAPP00000006015
annotation not available
     
 0.955
SGPP2
Sphingosine-1-phosphate phosphatase 2.
    
 0.953
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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