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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TBC1D8TBC1 domain family member 8. (1087 aa)    
Predicted Functional Partners:
GAK
Cyclin G associated kinase.
   
 
  0.980
ENSCAPP00000007793
annotation not available
   
 
  0.691
IGF2R
Insulin like growth factor 2 receptor.
   
 
  0.613
HIP1R
Huntingtin interacting protein 1 related.
   
 
  0.600
HIP1
Huntingtin interacting protein 1.
   
 
  0.572
AP2B1
Adaptor related protein complex 2 subunit beta 1.
   
 
  0.572
AP1B1
Adaptor related protein complex 1 subunit beta 1.
   
 
  0.572
TBC1D13
TBC1 domain family member 13.
     
 0.563
MIPOL1
Mirror-image polydactyly 1.
   
    0.556
TBC1D17
TBC1 domain family member 17.
      
 0.547
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.