STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TOP2ADNA topoisomerase II alpha. (1393 aa)    
Predicted Functional Partners:
CDK1
Cyclin dependent kinase 1.
   
 
 0.963
ENSCAPP00000011596
annotation not available
   
  
 0.959
UBE2C
Ubiquitin conjugating enzyme E2 C.
   
 0.949
ENSCAPP00000014267
annotation not available
   
  
 0.948
ESPL1
Extra spindle pole bodies like 1, separase.
   
 
 0.932
KIF20A
Kinesin family member 20A.
   
 
 0.926
ENSCAPP00000012564
annotation not available
   
  
 0.924
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
  
 0.921
CCNA2
Cyclin A2.
   
  
 0.921
TOP1MT
DNA topoisomerase I mitochondrial.
   
 
 0.921
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.