Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBFBCore-binding factor subunit beta. (100 aa)    
Predicted Functional Partners:
RUNX2
RUNX family transcription factor 2.
    
 0.988
CUL5
Cullin 5.
    
 
 0.981
ENSCAPP00000000033
annotation not available
    
 0.974
RUNX3
RUNX family transcription factor 3.
    
 0.974
ENSCAPP00000016562
annotation not available
    
 
 0.955
PRMT1
Protein arginine methyltransferase 1.
     
  0.918
ENSCAPP00000006058
annotation not available
     
  0.917
HIPK2
Homeodomain interacting protein kinase 2.
     
 0.912
ENSCAPP00000007958
annotation not available
    
  0.911
CDK6
Cyclin dependent kinase 6.
     
  0.905
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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