CLDN4 protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

CLDN4

Claudin 4. (209 aa)

Predicted Functional Partners:

TJP1

0.995

CLDN9

0.994

CLDN12

0.977

ENSCAPP00000002045

0.945

ENSCAPP00000006814

0.945

ENSCAPP00000015559

0.945

CLDN7

0.943

CLDN16

0.940

CLDN1

0.929

CLDN11

0.924

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLDN1	CLDN11	ENSCAPP00000013318	ENSCAPP00000005577	Claudin 1.	Claudin 11.	0.911
CLDN1	CLDN12	ENSCAPP00000013318	ENSCAPP00000011062	Claudin 1.	Claudin 12.	0.971
CLDN1	CLDN16	ENSCAPP00000013318	ENSCAPP00000013197	Claudin 1.	Claudin 16.	0.941
CLDN1	CLDN4	ENSCAPP00000013318	ENSCAPP00000002742	Claudin 1.	Claudin 4.	0.929
CLDN1	CLDN7	ENSCAPP00000013318	ENSCAPP00000008794	Claudin 1.	Claudin 7.	0.911
CLDN1	CLDN9	ENSCAPP00000013318	ENSCAPP00000005869	Claudin 1.	Claudin 9.	0.921
CLDN1	ENSCAPP00000002045	ENSCAPP00000013318	ENSCAPP00000002045	Claudin 1.	annotation not available	0.943
CLDN1	ENSCAPP00000006814	ENSCAPP00000013318	ENSCAPP00000006814	Claudin 1.	annotation not available	0.953
CLDN1	ENSCAPP00000015559	ENSCAPP00000013318	ENSCAPP00000015559	Claudin 1.	annotation not available	0.953
CLDN1	TJP1	ENSCAPP00000013318	ENSCAPP00000009772	Claudin 1.	Tight junction protein 1.	0.997
CLDN11	CLDN1	ENSCAPP00000005577	ENSCAPP00000013318	Claudin 11.	Claudin 1.	0.911
CLDN11	CLDN12	ENSCAPP00000005577	ENSCAPP00000011062	Claudin 11.	Claudin 12.	0.957
CLDN11	CLDN16	ENSCAPP00000005577	ENSCAPP00000013197	Claudin 11.	Claudin 16.	0.914
CLDN11	CLDN4	ENSCAPP00000005577	ENSCAPP00000002742	Claudin 11.	Claudin 4.	0.924
CLDN11	CLDN7	ENSCAPP00000005577	ENSCAPP00000008794	Claudin 11.	Claudin 7.	0.912
CLDN11	CLDN9	ENSCAPP00000005577	ENSCAPP00000005869	Claudin 11.	Claudin 9.	0.923
CLDN11	ENSCAPP00000002045	ENSCAPP00000005577	ENSCAPP00000002045	Claudin 11.	annotation not available	0.832
CLDN11	ENSCAPP00000006814	ENSCAPP00000005577	ENSCAPP00000006814	Claudin 11.	annotation not available	0.934
CLDN11	ENSCAPP00000015559	ENSCAPP00000005577	ENSCAPP00000015559	Claudin 11.	annotation not available	0.934
CLDN11	TJP1	ENSCAPP00000005577	ENSCAPP00000009772	Claudin 11.	Tight junction protein 1.	0.947