SETD4 protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

SETD4

SET domain containing 4. (407 aa)

Predicted Functional Partners:

PPP1R10

0.957

ENSCAPP00000000925

0.949

ENSCAPP00000011427

0.949

SLC5A7

0.949

KIAA1958

0.865

ENSCAPP00000012542

0.798

SUCLG2

0.794

RBKS

0.740

SUCLA2

0.725

ACLY

0.710

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACLY	SETD4	ENSCAPP00000011743	ENSCAPP00000002767	ATP citrate lyase.	SET domain containing 4.	0.710
ACLY	SUCLA2	ENSCAPP00000011743	ENSCAPP00000000454	ATP citrate lyase.	succinate-CoA ligase ADP-forming beta subunit.	0.877
ACLY	SUCLG2	ENSCAPP00000011743	ENSCAPP00000002539	ATP citrate lyase.	succinate-CoA ligase GDP-forming beta subunit.	0.804
ENSCAPP00000000925	ENSCAPP00000011427	ENSCAPP00000000925	ENSCAPP00000011427	annotation not available	annotation not available	0.883
ENSCAPP00000000925	PPP1R10	ENSCAPP00000000925	ENSCAPP00000001877	annotation not available	Protein phosphatase 1 regulatory subunit 10.	0.880
ENSCAPP00000000925	SETD4	ENSCAPP00000000925	ENSCAPP00000002767	annotation not available	SET domain containing 4.	0.949
ENSCAPP00000000925	SLC5A7	ENSCAPP00000000925	ENSCAPP00000017491	annotation not available	Solute carrier family 5 member 7.	0.933
ENSCAPP00000011427	ENSCAPP00000000925	ENSCAPP00000011427	ENSCAPP00000000925	annotation not available	annotation not available	0.883
ENSCAPP00000011427	PPP1R10	ENSCAPP00000011427	ENSCAPP00000001877	annotation not available	Protein phosphatase 1 regulatory subunit 10.	0.643
ENSCAPP00000011427	SETD4	ENSCAPP00000011427	ENSCAPP00000002767	annotation not available	SET domain containing 4.	0.949
ENSCAPP00000011427	SLC5A7	ENSCAPP00000011427	ENSCAPP00000017491	annotation not available	Solute carrier family 5 member 7.	0.882
ENSCAPP00000012542	RBKS	ENSCAPP00000012542	ENSCAPP00000009437	annotation not available	Ribokinase.	0.925
ENSCAPP00000012542	SETD4	ENSCAPP00000012542	ENSCAPP00000002767	annotation not available	SET domain containing 4.	0.798
KIAA1958	SETD4	ENSCAPP00000006235	ENSCAPP00000002767	KIAA1958.	SET domain containing 4.	0.865
PPP1R10	ENSCAPP00000000925	ENSCAPP00000001877	ENSCAPP00000000925	Protein phosphatase 1 regulatory subunit 10.	annotation not available	0.880
PPP1R10	ENSCAPP00000011427	ENSCAPP00000001877	ENSCAPP00000011427	Protein phosphatase 1 regulatory subunit 10.	annotation not available	0.643
PPP1R10	SETD4	ENSCAPP00000001877	ENSCAPP00000002767	Protein phosphatase 1 regulatory subunit 10.	SET domain containing 4.	0.957
PPP1R10	SLC5A7	ENSCAPP00000001877	ENSCAPP00000017491	Protein phosphatase 1 regulatory subunit 10.	Solute carrier family 5 member 7.	0.949
RBKS	ENSCAPP00000012542	ENSCAPP00000009437	ENSCAPP00000012542	Ribokinase.	annotation not available	0.925
RBKS	SETD4	ENSCAPP00000009437	ENSCAPP00000002767	Ribokinase.	SET domain containing 4.	0.740