Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TOB2Transducer of ERBB2, 2. (340 aa)    
Predicted Functional Partners:
CNOT7
CCR4-NOT transcription complex subunit 7.
    
 0.981
CNOT2
CCR4-NOT transcription complex subunit 2.
    
 0.975
ENSCAPP00000007441
annotation not available
    
 0.969
CNOT3
CCR4-NOT transcription complex subunit 3.
    
 0.968
CNOT6
CCR4-NOT transcription complex subunit 6.
    
 0.967
CNOT8
CCR4-NOT transcription complex subunit 8.
    
 0.964
ENSCAPP00000005548
annotation not available
    
 0.940
ENSCAPP00000012294
annotation not available
    
 0.940
ENSCAPP00000010706
annotation not available
    
 0.926
CNOT4
CCR4-NOT transcription complex subunit 4.
     
 0.878
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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