STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PEA15Proliferation and apoptosis adaptor protein 15. (130 aa)    
Predicted Functional Partners:
MAPK3
Mitogen-activated protein kinase 3.
    
 0.986
MAPK7
Mitogen-activated protein kinase 7.
    
 0.960
APAF1
Apoptotic peptidase activating factor 1.
    
 0.902
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
    
 0.878
APPL1
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.
    
 0.878
MAPK11
Mitogen-activated protein kinase 11.
    
 0.781
MAPK12
Mitogen-activated protein kinase 12.
    
 0.781
MAPK13
Mitogen-activated protein kinase 13.
    
 0.781
MAPK14
Mitogen-activated protein kinase 14.
    
 0.781
BIRC6
Baculoviral IAP repeat containing 6.
   
 0.752
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.