Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PLXNA4Plexin A4. (1312 aa)    
Predicted Functional Partners:
NRP1
Neuropilin 1.
    
 0.997
PLXNA2
Plexin A2.
   
 
  0.994
SEMA3A
Semaphorin 3A.
    
 0.993
SEMA6A
Semaphorin 6A.
    
 0.986
PLXND1
Plexin D1.
    
 0.971
PLXNA1
Plexin A1.
   
 
 0.968
ENSCAPP00000004294
annotation not available
    
 0.967
SEMA4D
Semaphorin 4D.
    
 0.963
PLXNA3
Plexin A3.
   
 
 0.963
PLXNB1
Plexin B1.
    
 0.961
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (12%) [HD]