close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCAPP00000002817annotation not available (244 aa)    
Predicted Functional Partners:
NCOA1
Nuclear receptor coactivator 1.
    
 0.980
NCOA2
Nuclear receptor coactivator 2.
    
 0.977
NCOA3
Nuclear receptor coactivator 3.
    
 0.976
ENSCAPP00000015240
annotation not available
    
 0.950
EP300
E1A binding protein p300.
    
 0.944
MED1
Mediator complex subunit 1.
    
 0.914
ESR2
Estrogen receptor 2.
    
0.913
ENSCAPP00000007887
annotation not available
 
      0.894
FOS
Fos proto-oncogene, AP-1 transcription factor subunit.
    
 0.883
ENSCAPP00000013163
annotation not available
    
 
 0.883
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.