Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ZWILCHZwilch kinetochore protein. (560 aa)    
Predicted Functional Partners:
ZW10
Zw10 kinetochore protein.
   
 0.999
KNTC1
Kinetochore associated 1.
   
 0.999
ENSCAPP00000008067
annotation not available
   
 
 0.962
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 0.920
ESPL1
Extra spindle pole bodies like 1, separase.
   
 
 0.900
MAD2L1
Mitotic arrest deficient 2 like 1.
   
 
 0.876
BUB3
BUB3 mitotic checkpoint protein.
     
 0.850
CDC20
Cell division cycle 20.
   
 
 0.826
NDC80
NDC80 kinetochore complex component.
   
 
 0.822
ENSCAPP00000013943
annotation not available
   
 
 0.811
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.