STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZWILCHZwilch kinetochore protein. (560 aa)    
Predicted Functional Partners:
KNTC1
Kinetochore associated 1.
   
 0.999
ZW10
Zw10 kinetochore protein.
    
 0.997
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 0.922
ESPL1
Extra spindle pole bodies like 1, separase.
   
 
 0.879
ENSCAPP00000012564
annotation not available
   
  
 0.869
BUB3
BUB3 mitotic checkpoint protein.
     
 0.822
MAD2L1
Mitotic arrest deficient 2 like 1.
   
 
 0.820
TTK
TTK protein kinase.
   
  
 0.816
ENSCAPP00000013943
annotation not available
   
 
 0.803
CDC20
Cell division cycle 20.
   
 
 0.792
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.