HELLS protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

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[Homology]

Score

HELLS

Helicase, lymphoid specific. (573 aa)

Predicted Functional Partners:

ENSCAPP00000018529

0.986

CDCA7

0.922

ENSCAPP00000010002

0.911

POLE3

0.869

BPTF

0.867

MYSM1

0.859

HDAC2

0.859

RAD51

0.849

POU5F2

0.841

TCEA3

0.840

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BPTF	HELLS	ENSCAPP00000010189	ENSCAPP00000002892	Bromodomain PHD finger transcription factor.	Helicase, lymphoid specific.	0.867
BPTF	POLE3	ENSCAPP00000010189	ENSCAPP00000005827	Bromodomain PHD finger transcription factor.	DNA polymerase epsilon 3, accessory subunit.	0.956
CDCA7	HELLS	ENSCAPP00000016901	ENSCAPP00000002892	Cell division cycle associated 7.	Helicase, lymphoid specific.	0.922
CDCA7	TCEA3	ENSCAPP00000016901	ENSCAPP00000014982	Cell division cycle associated 7.	Transcription elongation factor A3.	0.820
ENSCAPP00000010002	HDAC2	ENSCAPP00000010002	ENSCAPP00000016491	annotation not available	Histone deacetylase 2.	0.938
ENSCAPP00000010002	HELLS	ENSCAPP00000010002	ENSCAPP00000002892	annotation not available	Helicase, lymphoid specific.	0.911
ENSCAPP00000018529	HELLS	ENSCAPP00000018529	ENSCAPP00000002892	annotation not available	Helicase, lymphoid specific.	0.986
ENSCAPP00000018529	MYSM1	ENSCAPP00000018529	ENSCAPP00000004064	annotation not available	Myb like, SWIRM and MPN domains 1.	0.705
ENSCAPP00000018529	POLE3	ENSCAPP00000018529	ENSCAPP00000005827	annotation not available	DNA polymerase epsilon 3, accessory subunit.	0.426
ENSCAPP00000018529	RAD51	ENSCAPP00000018529	ENSCAPP00000003988	annotation not available	RAD51 recombinase.	0.629
HDAC2	ENSCAPP00000010002	ENSCAPP00000016491	ENSCAPP00000010002	Histone deacetylase 2.	annotation not available	0.938
HDAC2	HELLS	ENSCAPP00000016491	ENSCAPP00000002892	Histone deacetylase 2.	Helicase, lymphoid specific.	0.859
HDAC2	MYSM1	ENSCAPP00000016491	ENSCAPP00000004064	Histone deacetylase 2.	Myb like, SWIRM and MPN domains 1.	0.534
HDAC2	POU5F2	ENSCAPP00000016491	ENSCAPP00000004974	Histone deacetylase 2.	POU domain class 5, transcription factor 2.	0.880
HELLS	BPTF	ENSCAPP00000002892	ENSCAPP00000010189	Helicase, lymphoid specific.	Bromodomain PHD finger transcription factor.	0.867
HELLS	CDCA7	ENSCAPP00000002892	ENSCAPP00000016901	Helicase, lymphoid specific.	Cell division cycle associated 7.	0.922
HELLS	ENSCAPP00000010002	ENSCAPP00000002892	ENSCAPP00000010002	Helicase, lymphoid specific.	annotation not available	0.911
HELLS	ENSCAPP00000018529	ENSCAPP00000002892	ENSCAPP00000018529	Helicase, lymphoid specific.	annotation not available	0.986
HELLS	HDAC2	ENSCAPP00000002892	ENSCAPP00000016491	Helicase, lymphoid specific.	Histone deacetylase 2.	0.859
HELLS	MYSM1	ENSCAPP00000002892	ENSCAPP00000004064	Helicase, lymphoid specific.	Myb like, SWIRM and MPN domains 1.	0.859