close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HELLSHelicase, lymphoid specific. (573 aa)    
Predicted Functional Partners:
POLE3
DNA polymerase epsilon 3, accessory subunit.
    
 0.928
BPTF
Bromodomain PHD finger transcription factor.
    
 0.915
LEO1
LEO1 homolog, Paf1/RNA polymerase II complex component.
    
 0.915
ENSCAPP00000001550
annotation not available
   
 0.903
EXO1
Exonuclease 1.
   
 0.886
ENSCAPP00000018529
annotation not available
   
 0.867
ATAD2
ATPase family AAA domain containing 2.
   
 
 0.848
CDC6
Cell division cycle 6.
   
 
 0.833
H2AZ2
H2A.Z variant histone 2.
   
 0.808
ENSCAPP00000007768
annotation not available
    
 0.789
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.