DNASE1L3 protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

DNASE1L3

Deoxyribonuclease 1 like 3. (251 aa)

Predicted Functional Partners:

ENSCAPP00000015096

0.724

SIN3B

0.704

SIN3A

0.704

ENSCAPP00000005717

0.656

ENSCAPP00000013045

0.635

RRAGC

0.633

CHUK

0.631

TBK1

0.631

IKBKB

0.631

IKBKE

0.631

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHUK	DNASE1L3	ENSCAPP00000000766	ENSCAPP00000002919	Component of inhibitor of nuclear factor kappa B kinase complex.	Deoxyribonuclease 1 like 3.	0.631
CHUK	ENSCAPP00000005717	ENSCAPP00000000766	ENSCAPP00000005717	Component of inhibitor of nuclear factor kappa B kinase complex.	annotation not available	0.429
CHUK	ENSCAPP00000015096	ENSCAPP00000000766	ENSCAPP00000015096	Component of inhibitor of nuclear factor kappa B kinase complex.	annotation not available	0.847
CHUK	IKBKB	ENSCAPP00000000766	ENSCAPP00000004955	Component of inhibitor of nuclear factor kappa B kinase complex.	Inhibitor of nuclear factor kappa B kinase subunit beta.	0.997
CHUK	IKBKE	ENSCAPP00000000766	ENSCAPP00000010198	Component of inhibitor of nuclear factor kappa B kinase complex.	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	0.683
CHUK	RRAGC	ENSCAPP00000000766	ENSCAPP00000006157	Component of inhibitor of nuclear factor kappa B kinase complex.	Ras related GTP binding C.	0.408
CHUK	TBK1	ENSCAPP00000000766	ENSCAPP00000000862	Component of inhibitor of nuclear factor kappa B kinase complex.	TANK binding kinase 1.	0.707
DNASE1L3	CHUK	ENSCAPP00000002919	ENSCAPP00000000766	Deoxyribonuclease 1 like 3.	Component of inhibitor of nuclear factor kappa B kinase complex.	0.631
DNASE1L3	ENSCAPP00000005717	ENSCAPP00000002919	ENSCAPP00000005717	Deoxyribonuclease 1 like 3.	annotation not available	0.656
DNASE1L3	ENSCAPP00000013045	ENSCAPP00000002919	ENSCAPP00000013045	Deoxyribonuclease 1 like 3.	annotation not available	0.635
DNASE1L3	ENSCAPP00000015096	ENSCAPP00000002919	ENSCAPP00000015096	Deoxyribonuclease 1 like 3.	annotation not available	0.724
DNASE1L3	IKBKB	ENSCAPP00000002919	ENSCAPP00000004955	Deoxyribonuclease 1 like 3.	Inhibitor of nuclear factor kappa B kinase subunit beta.	0.631
DNASE1L3	IKBKE	ENSCAPP00000002919	ENSCAPP00000010198	Deoxyribonuclease 1 like 3.	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	0.631
DNASE1L3	RRAGC	ENSCAPP00000002919	ENSCAPP00000006157	Deoxyribonuclease 1 like 3.	Ras related GTP binding C.	0.633
DNASE1L3	SIN3A	ENSCAPP00000002919	ENSCAPP00000010185	Deoxyribonuclease 1 like 3.	SIN3 transcription regulator family member A.	0.704
DNASE1L3	SIN3B	ENSCAPP00000002919	ENSCAPP00000000416	Deoxyribonuclease 1 like 3.	SIN3 transcription regulator family member B.	0.704
DNASE1L3	TBK1	ENSCAPP00000002919	ENSCAPP00000000862	Deoxyribonuclease 1 like 3.	TANK binding kinase 1.	0.631
ENSCAPP00000005717	CHUK	ENSCAPP00000005717	ENSCAPP00000000766	annotation not available	Component of inhibitor of nuclear factor kappa B kinase complex.	0.429
ENSCAPP00000005717	DNASE1L3	ENSCAPP00000005717	ENSCAPP00000002919	annotation not available	Deoxyribonuclease 1 like 3.	0.656
ENSCAPP00000005717	ENSCAPP00000013045	ENSCAPP00000005717	ENSCAPP00000013045	annotation not available	annotation not available	0.992