close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GIT1GIT ArfGAP 1. (759 aa)    
Predicted Functional Partners:
ARHGEF7
Rho guanine nucleotide exchange factor 7.
    
 0.982
PXN
Paxillin.
    
 0.981
ITSN2
Intersectin 2.
   
 
 0.980
LPXN
Leupaxin.
    
 0.960
GIT2
GIT ArfGAP 2.
  
 
0.869
ENSCAPP00000016074
annotation not available
    
 0.850
PAK2
P21 (RAC1) activated kinase 2.
    
 0.835
ENSCAPP00000000244
annotation not available
    
 0.827
ENSCAPP00000013002
annotation not available
    
 0.786
PPFIA2
PTPRF interacting protein alpha 2.
    
 
 0.772
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: high (90%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.