Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VPS28VPS28 subunit of ESCRT-I. (227 aa)    
Predicted Functional Partners:
VPS37A
VPS37A subunit of ESCRT-I.
   
 0.999
MVB12A
Multivesicular body subunit 12A.
   
 0.999
UBAP1
Ubiquitin associated protein 1.
    
 0.999
VPS36
Vacuolar protein sorting 36 homolog.
    
 0.999
SNF8
SNF8 subunit of ESCRT-II.
   
 0.999
VPS37B
VPS37B subunit of ESCRT-I.
    
 0.999
MVB12B
Multivesicular body subunit 12B.
   
 0.999
UEVLD
UEV and lactate/malate dehyrogenase domains.
   
 0.999
TSG101
Tumor susceptibility 101.
   
 0.999
STAM
Signal transducing adaptor molecule.
    
 0.999
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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