Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KEAP1Kelch like ECH associated protein 1. (411 aa)    
Predicted Functional Partners:
NFE2L2
Nuclear factor, erythroid 2 like 2.
    
 0.999
RBX1
Ring-box 1.
    
 0.998
CUL3
Cullin 3.
    
 0.998
SQSTM1
Sequestosome 1.
    
 0.988
NFE2L1
Nuclear factor, erythroid 2 like 1.
    
 0.983
PGAM5
PGAM family member 5, mitochondrial serine/threonine protein phosphatase.
    
 
 0.976
DPP3
Dipeptidyl peptidase 3.
    
 0.976
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
    
 
 0.974
KLHL3
Kelch like family member 3.
    
  0.974
ENSCAPP00000016271
annotation not available
    
 0.970
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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