STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NSMAFNeutral sphingomyelinase activation associated factor. (910 aa)    
Predicted Functional Partners:
SMPD2
Sphingomyelin phosphodiesterase 2.
     
 0.968
ENSCAPP00000005006
annotation not available
   
 0.890
TNFRSF25
TNF receptor superfamily member 25.
    
 0.835
PLEKHG6
Pleckstrin homology and RhoGEF domain containing G6.
    
 0.835
PLEKHG5
Pleckstrin homology and RhoGEF domain containing G5.
    
 0.835
PSMB3
Proteasome 20S subunit beta 3.
    
 
 0.777
ENSCAPP00000003907
annotation not available
 
   
 0.768
TNF
Tumor necrosis factor.
     
  0.735
RACK1
Receptor for activated C kinase 1.
    
 0.727
GABARAPL2
GABA type A receptor associated protein like 2.
    
 0.712
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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