STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NSMAFNeutral sphingomyelinase activation associated factor. (910 aa)    
Predicted Functional Partners:
SMPD2
Sphingomyelin phosphodiesterase 2.
     
 0.906
TNFRSF25
TNF receptor superfamily member 25.
    
 0.758
PLEKHG6
Pleckstrin homology and RhoGEF domain containing G6.
    
 0.758
PLEKHG5
Pleckstrin homology and RhoGEF domain containing G5.
    
 0.758
RACK1
Receptor for activated C kinase 1.
    
 0.739
ATG5
Autophagy related 5.
    
 0.686
TNF
Tumor necrosis factor.
     
 0.648
ATG12
Autophagy related 12.
    
 0.634
ENSCAPP00000003907
annotation not available
 
    
 0.602
PSMB3
Proteasome 20S subunit beta 3.
    
 
 0.594
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.