Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MINK1Misshapen like kinase 1. (1322 aa)    
Predicted Functional Partners:
MAP4K4
Mitogen-activated protein kinase kinase kinase kinase 4.
   
  0.996
TNIK
TRAF2 and NCK interacting kinase.
   
  0.994
NCK2
NCK adaptor protein 2.
    
 
 0.870
STRN4
Striatin 4.
   
 
 0.864
MAP3K1
Mitogen-activated protein kinase kinase kinase 1.
    
 0.861
STRN3
Striatin 3.
    
 
 0.855
STRIP1
Striatin interacting protein 1.
    
 
 0.848
ENSCAPP00000016992
annotation not available
    
   0.824
LATS1
Large tumor suppressor kinase 1.
    
 
 0.798
ENSCAPP00000008321
annotation not available
     
 0.795
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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