Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADAM10ADAM metallopeptidase domain 10. (722 aa)    
Predicted Functional Partners:
TSPAN33
Tetraspanin 33.
    
 0.958
TSPAN15
Tetraspanin 15.
    
 0.958
CD9
CD9 molecule.
    
 0.947
MERTK
MER proto-oncogene, tyrosine kinase.
    
 0.943
ADAM17
ADAM metallopeptidase domain 17.
     
 0.928
HBEGF
Heparin binding EGF like growth factor.
    
 0.925
TSPAN14
Tetraspanin 14.
   
 0.925
TSPAN5
Tetraspanin 5.
   
 0.922
C8A
Complement C8 alpha chain.
     
  0.913
PPIF
Peptidylprolyl isomerase F.
     
  0.913
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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