Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SORBS2Sorbin and SH3 domain containing 2. (1067 aa)    
Predicted Functional Partners:
VCL
Vinculin.
   
 0.976
ENSCAPP00000013675
annotation not available
    
 0.943
AFDN
Afadin, adherens junction formation factor.
    
 0.856
FLOT1
Flotillin 1.
    
 0.849
FLOT2
Flotillin 2.
    
  0.847
GCH1
GTP cyclohydrolase 1.
    
   0.835
CBLB
Cbl proto-oncogene B.
    
 0.834
SYNJ1
Synaptojanin 1.
    
 
 0.816
SYNGAP1
Synaptic Ras GTPase activating protein 1.
    
   0.815
ENSCAPP00000009903
annotation not available
    
 
 0.802
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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