Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FAM49AFamily with sequence similarity 49 member A. (312 aa)    
Predicted Functional Partners:
FAM49B
Family with sequence similarity 49 member B.
   
  0.999
ENSCAPP00000006843
annotation not available
      
 0.924
RAC1
Rac family small GTPase 1.
    
 0.905
RAC2
Rac family small GTPase 2.
    
 0.905
RAC3
Rac family small GTPase 3.
    
 0.901
APLP2
Amyloid beta precursor like protein 2.
     
 0.657
ZBTB44
Zinc finger and BTB domain containing 44.
      
 0.656
RHOG
Ras homolog family member G.
   
 0.608
ENSCAPP00000009712
annotation not available
    
 0.601
RHOV
Ras homolog family member V.
    
 0.601
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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