Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PMEPA1Prostate transmembrane protein, androgen induced 1. (249 aa)    
Predicted Functional Partners:
ENSCAPP00000011344
annotation not available
    
 
 0.937
SMAD2
SMAD family member 2.
    
 0.910
ENSCAPP00000002730
annotation not available
    
 0.900
SMURF1
SMAD specific E3 ubiquitin protein ligase 1.
    
   0.877
WWP2
WW domain containing E3 ubiquitin protein ligase 2.
    
 
 0.876
ENSCAPP00000001550
annotation not available
    
 0.850
NEDD4L
NEDD4 like E3 ubiquitin protein ligase.
    
 
 0.810
PRMT5
Protein arginine methyltransferase 5.
   
 0.778
SMURF2
SMAD specific E3 ubiquitin protein ligase 2.
    
 
 0.768
FBLL1
Fibrillarin like 1.
   
 
 0.750
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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