Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TRMOtRNA methyltransferase O. (372 aa)    
Predicted Functional Partners:
HSBP1L1
Heat shock factor binding protein 1 like 1.
    
   0.855
ENSCAPP00000008186
annotation not available
      
 0.667
VPS37C
VPS37C subunit of ESCRT-I.
      
 0.664
SEC22A
SEC22 homolog A, vesicle trafficking protein.
      
 0.663
RAB14
RAB14, member RAS oncogene family.
    
   0.622
ITPA
Inosine triphosphatase.
    
  0.609
RHPN2
Rhophilin Rho GTPase binding protein 2.
    
   0.599
TNKS
Tankyrase.
    
   0.585
TNKS2
Tankyrase 2.
    
   0.585
ENSCAPP00000012840
annotation not available
   
  
 0.575
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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