PINK1 protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

PINK1

PTEN induced kinase 1. (451 aa)

Predicted Functional Partners:

ENSCAPP00000001899

0.996

ENSCAPP00000012837

0.996

TOMM40

0.995

ENSCAPP00000008030

0.985

TOMM70

0.985

BCL2L1

0.984

ENSCAPP00000011409

0.983

MFN2

0.982

ENSCAPP00000005383

0.977

PARK7

0.975

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCL2L1	ENSCAPP00000001899	ENSCAPP00000011244	ENSCAPP00000001899	BCL2 like 1.	annotation not available	0.913
BCL2L1	ENSCAPP00000005383	ENSCAPP00000011244	ENSCAPP00000005383	BCL2 like 1.	annotation not available	0.997
BCL2L1	ENSCAPP00000012837	ENSCAPP00000011244	ENSCAPP00000012837	BCL2 like 1.	annotation not available	0.913
BCL2L1	MFN2	ENSCAPP00000011244	ENSCAPP00000003987	BCL2 like 1.	Mitofusin 2.	0.696
BCL2L1	PARK7	ENSCAPP00000011244	ENSCAPP00000000476	BCL2 like 1.	Parkinsonism associated deglycase.	0.932
BCL2L1	PINK1	ENSCAPP00000011244	ENSCAPP00000003089	BCL2 like 1.	PTEN induced kinase 1.	0.984
ENSCAPP00000001899	BCL2L1	ENSCAPP00000001899	ENSCAPP00000011244	annotation not available	BCL2 like 1.	0.913
ENSCAPP00000001899	ENSCAPP00000005383	ENSCAPP00000001899	ENSCAPP00000005383	annotation not available	annotation not available	0.908
ENSCAPP00000001899	ENSCAPP00000008030	ENSCAPP00000001899	ENSCAPP00000008030	annotation not available	annotation not available	0.950
ENSCAPP00000001899	ENSCAPP00000011409	ENSCAPP00000001899	ENSCAPP00000011409	annotation not available	annotation not available	0.780
ENSCAPP00000001899	ENSCAPP00000012837	ENSCAPP00000001899	ENSCAPP00000012837	annotation not available	annotation not available	0.709
ENSCAPP00000001899	MFN2	ENSCAPP00000001899	ENSCAPP00000003987	annotation not available	Mitofusin 2.	0.994
ENSCAPP00000001899	PARK7	ENSCAPP00000001899	ENSCAPP00000000476	annotation not available	Parkinsonism associated deglycase.	0.982
ENSCAPP00000001899	PINK1	ENSCAPP00000001899	ENSCAPP00000003089	annotation not available	PTEN induced kinase 1.	0.996
ENSCAPP00000001899	TOMM40	ENSCAPP00000001899	ENSCAPP00000012183	annotation not available	Translocase of outer mitochondrial membrane 40.	0.980
ENSCAPP00000001899	TOMM70	ENSCAPP00000001899	ENSCAPP00000014910	annotation not available	Translocase of outer mitochondrial membrane 70.	0.990
ENSCAPP00000005383	BCL2L1	ENSCAPP00000005383	ENSCAPP00000011244	annotation not available	BCL2 like 1.	0.997
ENSCAPP00000005383	ENSCAPP00000001899	ENSCAPP00000005383	ENSCAPP00000001899	annotation not available	annotation not available	0.908
ENSCAPP00000005383	ENSCAPP00000008030	ENSCAPP00000005383	ENSCAPP00000008030	annotation not available	annotation not available	0.917
ENSCAPP00000005383	ENSCAPP00000011409	ENSCAPP00000005383	ENSCAPP00000011409	annotation not available	annotation not available	0.824