Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAPPA2Pappalysin 2. (1376 aa)    
Predicted Functional Partners:
IGFBP5
Insulin like growth factor binding protein 5.
    
 0.842
ENSCAPP00000017718
annotation not available
    
 
 0.779
STC2
Stanniocalcin 2.
    
 
 0.727
ENSCAPP00000002614
annotation not available
     
  0.677
UBE2V1
Ubiquitin conjugating enzyme E2 V1.
     
  0.677
ENSCAPP00000006605
annotation not available
    
 0.624
ENSCAPP00000014622
annotation not available
     
 0.603
IGFBP4
Insulin like growth factor binding protein 4.
    
 0.603
EYA1
EYA transcriptional coactivator and phosphatase 1.
      
 0.602
PLA2G4A
Phospholipase A2 group IVA.
     
  0.589
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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