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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WDR4WD repeat domain 4. (374 aa)    
Predicted Functional Partners:
METTL1
Methyltransferase like 1.
   
 0.999
TRMT61A
tRNA methyltransferase 61A.
   
 
 0.991
TRMT6
tRNA methyltransferase 6.
   
 0.977
TRMT11
tRNA methyltransferase 11 homolog.
   
 
 0.975
BUD23
BUD23 rRNA methyltransferase and ribosome maturation factor.
   
 
 0.962
TRMT10B
tRNA methyltransferase 10B.
   
 0.949
TRMT10A
tRNA methyltransferase 10A.
   
 0.949
PUS1
Pseudouridine synthase 1.
   
 
 0.932
ENSCAPP00000018577
annotation not available
   
  
 0.889
BOP1
BOP1 ribosomal biogenesis factor.
   
    0.852
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.