Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSCAPP00000003139annotation not available (879 aa)    
Predicted Functional Partners:
ENSCAPP00000006806
annotation not available
    
 0.989
JAK2
Janus kinase 2.
   
 0.989
JAK1
Janus kinase 1.
    
 0.977
IL5
Interleukin 5.
    
 0.972
JAK3
Janus kinase 3.
   
 0.969
PTPN11
Protein tyrosine phosphatase non-receptor type 11.
   
  0.947
PTPN6
Protein tyrosine phosphatase non-receptor type 6.
   
 0.916
TYK2
Tyrosine kinase 2.
    
 0.908
SHC1
SHC adaptor protein 1.
    
  0.906
ENSCAPP00000005717
annotation not available
  
  
 0.888
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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