Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DENND5BDENN domain containing 5B. (1138 aa)    
Predicted Functional Partners:
DENND4C
DENN domain containing 4C.
    
 0.976
DENND5A
DENN domain containing 5A.
   
   0.973
DENND3
DENN domain containing 3.
    
 0.923
SLC24A3
Solute carrier family 24 member 3.
   
  
 0.913
DENND4B
DENN domain containing 4B.
    
 0.877
DENND2B
DENN domain containing 2B.
    
 
 0.845
MADD
MAP kinase activating death domain.
    
   0.839
DENND4A
DENN domain containing 4A.
    
 0.836
VPS26A
VPS26, retromer complex component A.
     
 0.809
SNX1
Sorting nexin 1.
     
 0.804
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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