STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DENND5BDENN domain containing 5B. (1138 aa)    
Predicted Functional Partners:
ANKFY1
Ankyrin repeat and FYVE domain containing 1.
    
  0.989
DENND4C
DENN domain containing 4C.
    
0.910
SNX1
Sorting nexin 1.
     
 0.831
VPS35
VPS35 retromer complex component.
   
 
  0.810
SNX8
Sorting nexin 8.
     
 0.806
RAB7A
RAB7A, member RAS oncogene family.
     
 0.805
DENND4B
DENN domain containing 4B.
    
 0.777
DENND4A
DENN domain containing 4A.
    
 0.717
DENND3
DENN domain containing 3.
    
0.710
ENSCAPP00000006216
annotation not available
    
 
 0.649
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.