Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSCAPP00000003241annotation not available (434 aa)    
Predicted Functional Partners:
STAT3
Signal transducer and activator of transcription 3.
   
 0.971
LCP2
Lymphocyte cytosolic protein 2.
   
 0.954
BLNK
B cell linker.
    
 0.946
PRDM1
PR/SET domain 1.
    
 0.945
RUFY1
RUN and FYVE domain containing 1.
    
 0.938
SYK
Spleen associated tyrosine kinase.
   
 0.927
PLCG2
Phospholipase C gamma 2.
   
 0.924
PLCG1
Phospholipase C gamma 1.
   
 0.924
PTPN6
Protein tyrosine phosphatase non-receptor type 6.
   
 0.904
PIK3CA
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha.
    
 0.902
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (16%) [HD]