STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PCSK9Proprotein convertase subtilisin/kexin type 9. (620 aa)    
Predicted Functional Partners:
LDLR
Low density lipoprotein receptor.
    
 0.965
ENSCAPP00000017001
annotation not available
    
 0.932
PI4KA
Phosphatidylinositol 4-kinase alpha.
    
 0.919
VLDLR
Very low density lipoprotein receptor.
    
 0.908
SPTLC1
Serine palmitoyltransferase long chain base subunit 1.
   
 0.905
INPPL1
Inositol polyphosphate phosphatase like 1.
    
 0.885
LRP8
LDL receptor related protein 8.
    
 0.865
ENSCAPP00000009203
annotation not available
    
   0.853
ENSCAPP00000000068
annotation not available
    
 
 0.849
PI4KB
Phosphatidylinositol 4-kinase beta.
    
 0.832
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.