Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSCAPP00000003297annotation not available (407 aa)    
Predicted Functional Partners:
PPM1A
Protein phosphatase, Mg2+/Mn2+ dependent 1A.
   
   0.996
ISG15
ISG15 ubiquitin like modifier.
   
 0.985
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
  
 0.961
ENSCAPP00000013086
annotation not available
  
 0.937
MAP2K4
Mitogen-activated protein kinase kinase 4.
    
 0.877
MAP2K7
Mitogen-activated protein kinase kinase 7.
   
  0.869
PREPL
Prolyl endopeptidase like.
   
  
 0.849
ARRB2
Arrestin beta 2.
    
   0.839
TBK1
TANK binding kinase 1.
  
 0.838
GHRH
Growth hormone releasing hormone.
   
    0.826
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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