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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TXNDC12Thioredoxin domain containing 12. (148 aa)    
Predicted Functional Partners:
PRDX6
Peroxiredoxin 6.
  
 0.929
MGST3
Microsomal glutathione S-transferase 3.
    
  0.923
ENSCAPP00000010723
annotation not available
    
  0.916
GSR
Glutathione-disulfide reductase.
   
  0.915
GPX7
Glutathione peroxidase 7.
    
  0.912
GPX6
Glutathione peroxidase 6.
    
  0.912
GGT6
Gamma-glutamyltransferase 6.
     
 0.907
CHAC1
ChaC glutathione specific gamma-glutamylcyclotransferase 1.
     
 0.907
CHAC2
ChaC cation transport regulator homolog 2.
     
 0.907
GGT7
Gamma-glutamyltransferase 7.
     
 0.907
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.