Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SQLESqualene epoxidase. (449 aa)    
Predicted Functional Partners:
MSMO1
Methylsterol monooxygenase 1.
   
 0.994
NSDHL
NAD(P) dependent steroid dehydrogenase-like.
   
 
 0.992
FDFT1
Farnesyl-diphosphate farnesyltransferase 1.
 
 
 0.990
FAXDC2
Fatty acid hydroxylase domain containing 2.
   
 0.986
DHCR7
7-dehydrocholesterol reductase.
   
 
 0.981
MARCHF6
Membrane associated ring-CH-type finger 6.
    
 
 0.975
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1.
   
  
 0.974
ENSCAPP00000012173
annotation not available
   
  
 0.974
ENSCAPP00000005200
annotation not available
   
  
 0.960
TM7SF2
Transmembrane 7 superfamily member 2.
   
 
 0.923
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.