STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SQLESqualene epoxidase. (449 aa)    
Predicted Functional Partners:
MSMO1
Methylsterol monooxygenase 1.
   
 0.995
FAXDC2
Fatty acid hydroxylase domain containing 2.
   
 0.994
FDFT1
Farnesyl-diphosphate farnesyltransferase 1.
 
 
 0.986
NSDHL
NAD(P) dependent steroid dehydrogenase-like.
   
 
 0.977
DHCR7
7-dehydrocholesterol reductase.
   
 
 0.952
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1.
   
  
 0.941
SC5D
sterol-C5-desaturase.
   
 0.940
ENSCAPP00000005200
annotation not available
   
  
 0.935
ENSCAPP00000012173
annotation not available
   
  
 0.932
HMGCS2
3-hydroxy-3-methylglutaryl-CoA synthase 2.
   
  
 0.925
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.