Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PLCG2Phospholipase C gamma 2. (1242 aa)    
Predicted Functional Partners:
ENSCAPP00000010050
annotation not available
   
 0.997
EGFR
Epidermal growth factor receptor.
    
 0.996
ERBB2
Erb-b2 receptor tyrosine kinase 2.
    
 0.996
LCP2
Lymphocyte cytosolic protein 2.
   
 0.995
LAT
Linker for activation of T cells.
    
 0.994
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.989
SYK
Spleen associated tyrosine kinase.
   
 0.988
NTRK2
Neurotrophic receptor tyrosine kinase 2.
    
 0.987
PDGFRB
Platelet derived growth factor receptor beta.
    
 0.987
SH3BP2
SH3 domain binding protein 2.
    
 0.977
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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