Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DCAF1DDB1 and CUL4 associated factor 1. (1350 aa)    
Predicted Functional Partners:
CUL4A
Cullin 4A.
   
 0.999
DDB1
Damage specific DNA binding protein 1.
   
 0.999
RBX1
Ring-box 1.
    
 0.998
DDA1
DET1 and DDB1 associated 1.
    
 0.998
COPS8
COP9 signalosome subunit 8.
    
 0.996
COPS3
COP9 signalosome subunit 3.
    
 0.996
COPS6
COP9 signalosome subunit 6.
    
 0.996
COPS4
COP9 signalosome subunit 4.
    
 0.995
COPS7B
COP9 signalosome subunit 7B.
    
  0.995
COPS7A
COP9 signalosome subunit 7A.
    
  0.994
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.