STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CASP10Caspase 10. (494 aa)    
Predicted Functional Partners:
RIPK1
Receptor interacting serine/threonine kinase 1.
   
 0.984
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
    
 0.983
APPL1
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.
    
 0.983
CFLAR
CASP8 and FADD like apoptosis regulator.
   
0.978
APAF1
Apoptotic peptidase activating factor 1.
    
 0.978
TRADD
TNFRSF1A associated via death domain.
    
 0.939
ENSCAPP00000008032
annotation not available
   
 0.906
CYLD
CYLD lysine 63 deubiquitinase.
    
 0.895
CASP6
Caspase 6.
   
0.881
TRAF2
TNF receptor associated factor 2.
    
 0.878
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.