close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERCC4ERCC excision repair 4, endonuclease catalytic subunit. (817 aa)    
Predicted Functional Partners:
ERCC1
ERCC excision repair 1, endonuclease non-catalytic subunit.
   
 0.999
WRN
WRN RecQ like helicase.
    
 0.998
ENSCAPP00000010526
annotation not available
    
 0.997
FANCL
FA complementation group L.
    
 0.995
TOP3A
DNA topoisomerase III alpha.
    
 0.993
ENSCAPP00000007864
annotation not available
   
 0.991
MSH2
mutS homolog 2.
    
 0.988
MSH6
mutS homolog 6.
   
 0.977
ENSCAPP00000013410
annotation not available
    
 0.977
ERCC3
ERCC excision repair 3, TFIIH core complex helicase subunit.
  
 0.975
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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