Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ERCC4ERCC excision repair 4, endonuclease catalytic subunit. (817 aa)    
Predicted Functional Partners:
ERCC1
ERCC excision repair 1, endonuclease non-catalytic subunit.
   
 0.999
ENSCAPP00000010526
annotation not available
    
 0.999
ERCC3
ERCC excision repair 3, TFIIH core complex helicase subunit.
  
 0.999
XPC
XPC complex subunit, DNA damage recognition and repair factor.
    
 0.995
ERCC2
ERCC excision repair 2, TFIIH core complex helicase subunit.
   
 0.992
ENSCAPP00000006310
annotation not available
     
 0.992
MUS81
MUS81 structure-specific endonuclease subunit.
    
 0.991
TOP3A
DNA topoisomerase III alpha.
    
 0.988
FANCL
FA complementation group L.
    
 0.984
ENSCAPP00000007864
annotation not available
   
 0.981
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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