Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPRY1Sprouty RTK signaling antagonist 1. (319 aa)    
Predicted Functional Partners:
ENSCAPP00000013675
annotation not available
    
 0.991
CBLB
Cbl proto-oncogene B.
    
 0.903
SPRY2
Sprouty RTK signaling antagonist 2.
   
  0.898
GRB2
Growth factor receptor bound protein 2.
    
 
 0.869
MDFI
MyoD family inhibitor.
    
 
 0.845
ZNF23
Zinc finger protein 23.
    
   0.833
PDGFC
Platelet derived growth factor C.
      
 0.732
ETV5
ETS variant transcription factor 5.
      
 0.711
CBLC
Cbl proto-oncogene C.
    
 0.663
COQ4
Coenzyme Q4.
      
 0.657
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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