STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRY1Sprouty RTK signaling antagonist 1. (319 aa)    
Predicted Functional Partners:
ENSCAPP00000013675
annotation not available
    
 0.804
CBLB
Cbl proto-oncogene B.
    
 0.757
CBLC
Cbl proto-oncogene C.
    
 0.734
GRB2
Growth factor receptor bound protein 2.
    
 
 0.721
SPRY2
Sprouty RTK signaling antagonist 2.
  
0.704
SPRY4
Sprouty RTK signaling antagonist 4.
   
0.654
ENSCAPP00000005376
annotation not available
    
  0.645
ENSCAPP00000014682
annotation not available
    
  0.628
EGF
Epidermal growth factor.
     
 0.615
ENSCAPP00000007687
annotation not available
      
 0.564
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.